SML0400
ML204
≥98% (HPLC)
别名:
4-Methyl-2-(1-piperidinyl)-quinoline
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 5 mg/mL at warmed (clear solution)
储存温度
2-8°C
SMILES字符串
Cc1cc(nc2ccccc12)N3CCCCC3
InChI
1S/C15H18N2/c1-12-11-15(17-9-5-2-6-10-17)16-14-8-4-3-7-13(12)14/h3-4,7-8,11H,2,5-6,9-10H2,1H3
InChI key
USYRQXDHKXGTCK-UHFFFAOYSA-N
相关类别
应用
4-methyl-2-(1- piperidinyl)-quinoline (ML204) has been used to attenuate Ewing sarcoma (EWS)-FLI1 activity in TC32 cells. It has also been used to attenuate scratching behavior evoked by α-Me-5HT in mice.
生化/生理作用
ML204 is a potent and selective TRPC4 channel inhibitor.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Ruizhi Zhang et al.
Polymers, 12(2) (2020-02-08)
In this study, we fabricated poly (methyl methacrylate) (PMMA) microcellular foams featuring tunable cellular structures and porosity, through adjusting the supercritical CO2 foaming conditions. Experimental testing and finite element model (FEM) simulations were conducted to systematically elucidate the influence of
Englerin A inhibits EWS-FLI1 DNA binding in Ewing sarcoma cells
Caropreso V, et al.
The Journal of Biological Chemistry, 291(19), 10058-10066 (2016)
Yun Zhu et al.
Chemico-biological interactions, 260, 84-90 (2016-11-08)
Aflatoxins are fungal metabolites which pose a major threat to food safety. Although these mycotoxins are established hepatocarcinogens, their effect on the reproductive organ is unknown. Transient Receptor Potential Channels (TRPs) are ubiquitously expressed in human tissues, including the placenta.
Laura Bernal et al.
Science advances, 7(13) (2021-03-28)
Teeth are composed of many tissues, covered by an inflexible and obdurate enamel. Unlike most other tissues, teeth become extremely cold sensitive when inflamed. The mechanisms of this cold sensation are not understood. Here, we clarify the molecular and cellular
H M-H Chin et al.
Journal of helminthology, 91(4), 470-478 (2016-06-11)
Terrestrial arthropods host a variety of helminth parasites, yet quantifying the intensity of infection in these hosts post-mortem is challenging because carcasses may desiccate quickly. We recovered cysticercoids of Hymenolepis diminuta from desiccated flour beetle (Tribolium confusum) carcasses by modifying
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