SML0436
BNS-22
≥98% (HPLC)
别名:
8-[(3,4-Dihydro-2H-quinolin-1-yl)carbonyl]-5,7-dimethoxy-4-propyl-2H-chromen-2-one
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关于此项目
经验公式（希尔记法）:
C24H25NO5
化学文摘社编号:
分子量:
407.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C24H25NO5/c1-4-8-16-13-20(26)30-23-21(16)18(28-2)14-19(29-3)22(23)24(27)25-12-7-10-15-9-5-6-11-17(15)25/h5-6,9,11,13-14H,4,7-8,10,12H2,1-3H3
SMILES string
COC1=C2C(OC(C=C2CCC)=O)=C(C(N3C(C=CC=C4)=C4CCC3)=O)C(OC)=C1
InChI key
LRPUQCTZOSTSGL-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL (clear solution; warmed)
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
BNS-22 is a DNA-topoisomerase II (TOPO2) catalytic inhibitor.
BNS-22 is a derivative of natural product GUT-70 isolated from the stem bark of Calophyllum brasiliense exhibits antiproliferative activity against human cancer cells. It appears that BNS-22 is a specific DNA-topoisomerase II (TOPO2) catalytic inhibitor. BNS-22 does not induce DNA damage.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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