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Merck
CN

SML0437

氧雄龙

≥98% (HPLC)

别名:

17β-羟基-17α-甲基-2-氧杂-5α--雄烷-3-酮, 8075CB, NSC 67068, SC 11585, 奥克西伦, 氧甲氢龙

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关于此项目

经验公式(希尔记法):
C19H30O3
化学文摘社编号:
分子量:
306.44
EC 号:
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77
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质量水平

方案

≥98% (HPLC)

表单

powder

旋光性

[α]/D -19 to -26°, c = 1 (CDCl3)

药品控制

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

颜色

white to beige

溶解性

DMSO: 2 mg/mL (clear solution; warmed)

储存温度

2-8°C

SMILES字符串

C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4CC(=O)OC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C19H30O3/c1-17-11-22-16(20)10-12(17)4-5-13-14(17)6-8-18(2)15(13)7-9-19(18,3)21/h12-15,21H,4-11H2,1-3H3/t12-,13+,14-,15-,17-,18-,19-/m0/s1

InChI key

QSLJIVKCVHQPLV-PEMPUTJUSA-N

基因信息

human ... AR(367)

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生化/生理作用

氧甲氢龙是一种合成代谢类固醇。
氧甲氢龙是一种合成合成代谢类固醇。它是一种非芳香化雄激素,无雌激素样作用,具有轻度雄激素样活性。氧甲氢龙的临床应用包括促进大范围手术或慢性感染或创伤后体重减轻后的体重增加,抵消与长期管理皮质类固醇相关的蛋白质分解代谢,缓解经常伴随骨质疏松的骨痛,治疗女孩的特纳综合征。

特点和优势

该化合物是受体分类及信号转导手册上核受体(类固醇)页面上的特色化合物。想要浏览手册的其他页面, 请单击此处

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Carc. 2 - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Rhonda Orr et al.
Drugs, 64(7), 725-750 (2004-03-18)
There has been increasing interest in the development of effective agents that can be safely used to promote anabolism in the clinical setting for patients with chronic wasting conditions as well as in the prevention and treatment of frailty associated
Leonie A Menke et al.
Hormone research in paediatrics, 75(2), 115-122 (2010-09-04)
The weak androgen oxandrolone (Ox) may increase height but may also affect glucose metabolism in girls with Turner syndrome (TS). In a randomized, placebo-controlled, double-blind study, we assessed the effect of Ox at a dosage of either 0.06 or 0.03
Leonie A Menke et al.
Journal of voice : official journal of the Voice Foundation, 25(5), 602-610 (2010-10-26)
Oxandrolone (Ox) increases height gain but may also cause voice deepening in growth hormone (GH)-treated girls with Turner syndrome (TS). We assessed the effect of Ox on objective and subjective speaking voice frequency in GH-treated girls with TS. A multicenter
Yesenia Rojas et al.
Expert opinion on pharmacotherapy, 13(17), 2485-2494 (2012-11-06)
The worldwide occurrence of burn injuries remains high despite efforts to reduce injury incidence through public awareness campaigns and improvements in living conditions. In 2004, almost 11 million people experienced burns severe enough to warrant medical treatment. Advances over the
Martha P D Zeger et al.
Hormone research in paediatrics, 75(1), 38-46 (2010-08-25)
Untreated girls with Turner syndrome (TS) have growth failure, and adult height is, on average, 20 cm less than predicted height. Treatment with growth hormone (GH) is now standard of care. The objective of this study was to investigate the

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