Name: 多佐胺
Brand: SIGMA

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About This Item

经验公式（希尔记法）:

C₁₀H₁₆N₂O₄S₃

CAS Number:

120279-96-1

分子量:

324.44

MDL编号:

MFCD00865636

UNSPSC代码:

12352200

PubChem化学物质编号:

329824746

NACRES:

NA.77

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方案

≥98% (HPLC)

表单

powder

旋光性

[α]/D -25 to -35°, c = 1 in methanol

颜色

white to beige

溶解性

DMSO: 5 mg/mL (clear solution, warmed)

储存温度

room temp

SMILES字符串

CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O

InChI

1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m0/s1

InChI key

IAVUPMFITXYVAF-XPUUQOCRSA-N

基因信息

human ... CA2(760)

生化/生理作用

Dorzolamide is a potent carbonic anhydrase II inhibitor with an IC₅₀ value of 0.16 nM on human erythrocyte carbonic anhydrase II in vitro. It has been found to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.

Dorzolamide is a potent carbonic anhydrase II inhibitor.