SML0474
(S)-度洛西汀 盐酸盐
≥98% (HPLC), 5-HT and NA reuptake inhibitor, powder
别名:
(γS)-N-甲基-3-(萘-1-基氧)-3-(噻吩-2-基)丙烷-1-胺 盐酸盐, (+)-(S)-N-甲基-γ-(1-萘氧基)-2-噻吩丙胺 盐酸盐, (+)-N-甲基-3-(1-萘氧基)-3-(2-噻吩)-丙胺 盐酸盐, LY-248686 盐酸盐
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关于此项目
经验公式（希尔记法）:
C18H19NOS · HCl
化学文摘社编号:
分子量:
333.88
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
产品名称
(S)-度洛西汀 盐酸盐, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D +116 to +125°, c = 1 in methanol
storage condition
desiccated
color
white to beige
solubility
H2O: 5 mg/mL (clear solution, warmed)
storage temp.
room temp
SMILES string
Cl.CNCC[C@H](Oc1cccc2ccccc12)c3cccs3
InChI
1S/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/m0./s1
InChI key
BFFSMCNJSOPUAY-LMOVPXPDSA-N
Gene Information
human ... SLC6A2(6530), SLC6A4(6532)
General description
(S)-Duloxetine hydrochloride belongs to the class of serotonin and norepinephrine reuptake inhibitors. Duloxetine is a thiophene derivative. It is used to treat stress urinary incontinence, psychiatric and metabolic disorders. It is also used for treating diabetic peripheral neuropathic pain, fibromyalgia, chronic musculoskeletal and low back pain (LBP). Duloxetine is a cytochrome P450 2D6 (CYP2D6) inhibitor.
Application
(S)-Duloxetine hydrochloride has been used as an antidepressant in rats exposed to chronic mild stress (CMS).
Biochem/physiol Actions
盐酸度洛西汀是一种双重血清素/去甲肾上腺素再摄取抑制剂（SNRI），在临床上被广泛用作抗抑郁药和抗焦虑药。
盐酸度洛西汀是一种双重血清素/去甲肾上腺素再摄取抑制剂（SNRI）；抗抑郁药；抗焦虑药。
Features and Benefits
This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Disclaimer
air sensitive
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable