SML0475
CGP36742
≥97% (NMR)
别名:
P-(3-Aminopropyl)-P-butyl-phosphinic acid, SGS 742
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关于此项目
经验公式（希尔记法）:
C7H18NO2P
化学文摘社编号:
分子量:
179.20
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥97% (NMR)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥97% (NMR)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 10 mg/mL (clear solution, warmed)
storage temp.
room temp
SMILES string
CCCCP(O)(=O)CCCN
InChI
1S/C7H18NO2P/c1-2-3-6-11(9,10)7-4-5-8/h2-8H2,1H3,(H,9,10)
InChI key
ONNMDRQRSGKZCN-UHFFFAOYSA-N
Biochem/physiol Actions
CGP36742 is a GABAB receptor antagonist.
CGP36742 was the first orally active GABAB-selective antagonist. The IC50 for blocking GABAergic transmission is 36 μM. Oral administration of CGP36742 in rats blocks baclofen-induced neuronal depression, and reduces learning deficit and passive avoidance in an olfactory bulbectomy depression model.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable