Rabeprazole sodium

Name: Rabeprazole sodium
Brand: SIGMA

≥98% (HPLC)

别名:

2-([4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl)-1H-benzo[d]imidazole, Pariprazole

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About This Item

经验公式（希尔记法）:

C₁₈H₂₀N₃O₃S · Na

CAS Number:

117976-90-6

分子量:

381.42

UNSPSC代码:

12352200

PubChem化学物质编号:

329825431

NACRES:

NA.77

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to beige

溶解性

H₂O: 10 mg/mL (clear solution)

运输

wet ice

储存温度

−20°C

SMILES字符串

[Na+].COCCCOc1ccnc(CS(=O)c2nc3ccccc3[n-]2)c1C

InChI

1S/C18H20N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3;/q-1;+1

InChI key

KRCQSTCYZUOBHN-UHFFFAOYSA-N

基因信息

human ... ATP4A(495), ATP4B(496)

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应用

Rabeprazole sodium has been used as a proton pump inhibitor (PPI) to study its effects on spontaneous uterine contractile activity in pregnant women.

生化/生理作用

Rabeprazole sodium is gastric proton pump inhibitor. It suppresses the production of acid in the stomach by inhibiting the gastric H+/K+ATPase (hydrogen-potassium adenosine triphosphatase) at the secretory surface of the gastric parietal cell. Rabeprazole sodium has been used clinically to treat acid-reflux disorders (GERD), peptic ulcer disease, H. pylori eradication, and prevent gastroinetestinal bleeds associated with NSAID use.

Rabeprazole sodium is gastric proton pump inhibitor; antiulcerative.