SML0500
GSK334429 hydrochloride
≥98% (HPLC)
别名:
1-(1-Methylethyl)-4-((1-(6-(trifluoromethyl)-3-pyridinyl)-4-piperidinyl)carbonyl)hexahydro-1H-1,4-diazepine hydrochloride
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关于此项目
经验公式（希尔记法）:
C20H29F3N4O · xHCl
化学文摘社编号:
分子量:
398.47 (free base basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 5 mg/mL (clear solution)
storage temp.
2-8°C
SMILES string
Cl.CC(C)N1CCCN(CC1)C(=O)C2CCN(CC2)c3ccc(nc3)C(F)(F)F
InChI
1S/C20H29F3N4O.ClH/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23;/h4-5,14-16H,3,6-13H2,1-2H3;1H
InChI key
RCZVWLOXPFGZDD-UHFFFAOYSA-N
Biochem/physiol Actions
GSK334429 is a selective histamine H3 receptor antagonist.
GSK334429 is a selective histamine H3 receptor antagonist. H3 antagonists increase the release of brain histamine, ACh, NE and DA neurotransmitters that modulate cognitive processes. Studies look at their analgesic efffects including efficacy for neuropathic pain.
Features and Benefits
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Other Notes
Store desiccated; dry room.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable