SML0513
SKF83822 氢溴酸盐
别名:
6-Chloro-2,3,4,5-tetrahydro-1-(3-methylphenyl)-3-(2-propen-1-yl)-1H-3-Benzazepine-7,8-diol hydrobromide
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关于此项目
经验公式（希尔记法）:
C20H22ClNO2 · HBr
化学文摘社编号:
分子量:
424.76
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C20H22ClNO2.BrH/c1-3-8-22-9-7-15-16(11-18(23)20(24)19(15)21)17(12-22)14-6-4-5-13(2)10-14;/h3-6,10-11,17,23-24H,1,7-9,12H2,2H3;1H
SMILES string
Br.Cc1cccc(c1)C2CN(CCc3c(Cl)c(O)c(O)cc23)CC=C
InChI key
CFWPKYBBXBANLU-UHFFFAOYSA-N
storage temp.
2-8°C
Quality Level
相关类别
Biochem/physiol Actions
SKF83822 is a dopamine receptor agonist that only activates the D1 monomers and stimulates adenylate cyclase, but not PI hydrolysis.
SKF83822 is a dopamine receptor agonist that only activates the D1 monomers.
Features and Benefits
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Yuji Odagaki et al.
Journal of receptor and signal transduction research, 39(1), 9-17 (2019-06-22)
Although multiple roles of dopamine through D1-like (D1 and D5) and D2-like (D2, D3, and D4) receptors are initiated primarily through stimulation or inhibition of adenylyl cyclase via Gs/olf or Gi/o, respectively, there have been many reports indicating diverse signaling
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