SML0563
Docosahexaenoyl ethanolamide
≥98% (HPLC), ethanol solution (5 mg/ml)
别名:
(4Z,7Z,10Z,13Z,16Z,19Z)-N-(2-Hydroxyethyl)docosa-4,7,10,13,16,19-hexaenamide, DEA, DHEA, N-(2-Hydroxyethyl)-4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenamide, N-Docosahexaenoylethanolamide
产品名称
Docosahexaenoyl ethanolamide, ≥98% (HPLC), ethanol solution (5 mg/ml)
assay
≥98% (HPLC)
form
ethanol solution (5 mg/ml)
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
color
colorless to yellow
shipped in
dry ice
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Docosahexaenoyl ethanolamide (DHEA) has the ability to block the proliferation of head and neck squamous cell carcinoma (HNSCC) cell.
Docosahexaenoyl ethanolamide (DHEA) is a lipid signaling molecule present in brain and retina at concentrations, similar to those for arachidonoyl ethanolamide. DHEA binds to the rat brain CB1 receptor with a Ki of 324 nM. It exhibits anti-inflammatory and organ protective activity. Studies show that docosahexaenoyl ethanolamide is the mediator of neurite growth and synaptogenesis in hippocampal neurons, resulting in enhanced synaptic activity.
Docosahexaenoyl ethanolamide (DHEA), a lipid signaling molecule, binds to the rat brain CB1 receptor and exhibits anti-inflammatory and organ protective activity.
Features and Benefits
This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
55.4 °F
flash_point_c
13 °C
法规信息
新产品
此项目有
5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells
Park SW, et al.
BMC Cancer, 16(1), 458-458 (2016)
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