SML0617

A-804598

Name: A-804598
Brand: SIGMA

≥98% (HPLC)

别名:

N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine

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关于此项目

经验公式（希尔记法）:

C₁₉H₁₇N₅

化学文摘社编号:

1125758-85-1

分子量:

315.37

UNSPSC Code:

12352200

NACRES:

NA.77

主要文件

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SMILES string

N(c2c3c(nccc3)ccc2)\C(=N/[C@@H](C)c1ccccc1)\NC#N

InChI

1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1

InChI key

PQYCRDPLPKGSME-AWEZNQCLSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

A-804598 is a P2X7 selective, competitive antagonist.

A-804598 is a P2X7 selective, competitive antagonist. In competition assays, the IC₅₀s for human, rat and mouse channels are 11, 10 and 9 nM, respectively.

Features and Benefits

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.