方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
DMSO: 2 mg/mL, clear (warmed)
储存温度
2-8°C
SMILES字符串
NC(=NCCCCOC(=O)c1cc(c(c(c1)OC)O)OC)N
InChI
1S/C14H21N3O5/c1-20-10-7-9(8-11(21-2)12(10)18)13(19)22-6-4-3-5-17-14(15)16/h7-8,18H,3-6H2,1-2H3,(H4,15,16,17)
InChI key
WNGSUWLDMZFYNZ-UHFFFAOYSA-N
生化/生理作用
益母草碱 (SCM-198) 是一种天然产物，具有抗氧化、抗炎和正在研究治疗心血管疾病和中风的心脏保护活性。益母草碱抑制炎症和氧化应激，减少编号炎症因子，减少心肌 Nox4 的表达，减少 ROS 的产生，减少 NF- K B 的活化，减少血浆 MMP-2 的活性，增加超氧化物歧化酶 (SOD)。
益母草碱是一种抗氧化、抗炎的心脏保护剂。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Hong Xin et al.
Biological & pharmaceutical bulletin, 35(8), 1249-1256 (2012-08-07)
Leonurine (Leo) is a special alkaloid principle of Herba leonuri that has recently been suggested to improve cardiovascular functions. To date, there is no direct ionic evidence of Leo on regulating calcium channels in the heart. In the present study
Jia Qi et al.
Biological & pharmaceutical bulletin, 33(12), 1958-1964 (2010-12-09)
Ischemic brain is particularly susceptible to free radicals mediated secondary neuronal damage, especially mitochondrial dysfunctions. Chinese Herbal Medicine with antioxidant properties is believed to have potential therapeutic effect. Leonurine, an alkaloid present in Herba Leonuri (HL), has shown biological effects
Leonurine: a new comer in the natural compounds affecting atherosclerosis.
Giuseppe Danilo Norata et al.
Atherosclerosis, 224(1), 37-38 (2012-05-09)
Xin-hua Liu et al.
Journal of cardiovascular pharmacology, 54(5), 437-444 (2009-11-27)
In the present study, we examined the ability of a chemically synthesized compound based on the structure of leonurine, a phytochemical component of Herba leonuri, to protect H9c2 rat ventricular cells from apoptosis induced by hypoxia and serum deprivation, as
Effects of leonurine hydrochloride on medically induced incomplete abortion in early pregnancy rats.
Xia Li et al.
European journal of obstetrics, gynecology, and reproductive biology, 159(2), 375-380 (2011-10-28)
To determine the effect of leonurine hydrochloride (LH) on abnormal bleeding induced by medical abortion. Rats had incomplete abortions induced in early pregnancy using mifepristone in combination with misoprostol. After abortion, rats were treated with LH for 7 days, and
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