SML0699
4′-Methoxyflavone
≥97% (HPLC)
别名:
2-(4-Methoxyphenyl)-4H-chromen-4-one, 2-(4-Methoxyphenyl)chromone
SMILES string
[o]1c2c([c](cc1c3ccc(cc3)OC)=O)cccc2
InChI key
OMICQBVLCVRFGN-UHFFFAOYSA-N
InChI
1S/C16H12O3/c1-18-12-8-6-11(7-9-12)16-10-14(17)13-4-2-3-5-15(13)19-16/h2-10H,1H3
assay
≥97% (HPLC)
form
lyophilized powder
storage condition
protect from light
color
white
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
4-methoxyflavone is a neuroprotective agent that inhibits the accumulation of poly (ADP-ribose) and neuronal cell death following chemically-induced DNA damage or NMDA excitation.
4-methoxyflavone is a neuroprotective agent that is an inhibitor of PARP-1 mediated cell death (parthanatos).
Other Notes
Light sensitive.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
R N Gacche et al.
Archives of biochemistry and biophysics, 577-578, 35-48 (2015-05-06)
Relationship between structural diversity and biological activities of flavonoids has remained an important discourse in the mainstream of flavonoid research. In the current study anti-angiogenic, cytotoxic, antioxidant and cyclooxygenase (COX) inhibitory activities of diverse class of flavonoids including hydroxyl and
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