SML0720
醋甲唑胺
≥98% (HPLC), carbonic anhydrase inhibitor, powder
别名:
N-(4-甲基-2-氨基磺酰基-Δ2-1,3,4-噻二唑-5-亚基)乙酰胺
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关于此项目
经验公式（希尔记法）:
C5H8N4O3S2
化学文摘社编号:
分子量:
236.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
209-066-7
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
protect from light
产品名称
醋甲唑胺, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to beige
mp
208 °C (dec.) (lit.)
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
CN1N=C(S\C1=N\C(C)=O)S(N)(=O)=O
InChI
1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12)/b7-4+
InChI key
FLOSMHQXBMRNHR-QPJJXVBHSA-N
Biochem/physiol Actions
Methazolamide has a plasma half-life of 14 hours in humans. Methazolamide has relatively good lipid solubility and low plasma protein binding ability. Thus, it diffuses into tissues and fluids much more readily than acetazolamide, another carbonic anhydrase inhibitor. Methazolamide has less side effects than acetazolamide.
Cell-permeable and potent carbonic anhydrase (CA) inhibitor
Methazolamide is a cell-permeable and potent carbonic anhydrase (CA) inhibitor that is used in the treatment of glaucoma. Methazolamide is an insulin sensitizer that reduces hepatic glucose generation in animal models.
Other Notes
Light sensitive
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
存储类别
11 - Combustible Solids
wgk
WGK 3