SML0752
(+)-CP-99994 dihydrochloride
≥98% (HPLC), neurokinin (NK)-1 tachykinin antagonist, powder
别名:
(2S,3S)-3-(2-Methoxybenzylamino)-2-phenylpiperidine dihydrochloride, CP-99,994, CP-99994, CP99,994, CP99994
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关于此项目
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
产品名称
(+)-CP-99994 dihydrochloride, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 15 mg/mL, clear
storage temp.
2-8°C
SMILES string
[Cl-].[Cl-].[N+H2]1[C@H]([C@H](CCC1)[N+H2]Cc3c(cccc3)OC)c2ccccc2
InChI
1S/C19H24N2O.2ClH/c1-22-18-12-6-5-10-16(18)14-21-17-11-7-13-20-19(17)15-8-3-2-4-9-15;;/h2-6,8-10,12,17,19-21H,7,11,13-14H2,1H3;2*1H/t17-,19-;;/m0../s1
InChI key
WNHRFWPLRATIDT-FFUVTKDNSA-N
Biochem/physiol Actions
(+)-CP-99994 dihydrochloride is an effective and selective non-peptide substance P receptor antagonist. It is synthesized from allylic and homoallylic C-H diamination of 4-phenyl-1-butene. (+)-CP-99994 exhibits anti-emetic activity in ferrets.
(+)-CP-99994 is a selective neurokinin (NK)-1 tachykinin antagonist.
(+)-CP-99994 is a selective neurokinin (NK)-1 tachykinin antagonist. (+)-CP-99994 binds selectively and with high affinity with a Ki of 0.25 nM in a human cell line.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable