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SML0783

Sauchinone

Name: Sauchinone
Brand: SIGMA

≥98% (HPLC)

别名:

(5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one, (5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one

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关于此项目

经验公式（希尔记法）:

C₂₀H₂₀O₆

化学文摘社编号:

177931-17-8

分子量:

356.37

UNSPSC Code:

12352200

NACRES:

NA.77

MDL number:

MFCD08702698

Assay:

≥98% (HPLC)

Form:

powder

Quality level:

100

Storage condition:

desiccated

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属性

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

shipped in

wet ice

storage temp.

2-8°C

SMILES string

O=C(C=C1OCO2)[C@]3([H])C[C@@H](C)[C@H](C)[C@@]4([H])C5=CC6=C(OCO6)C=C5O[C@]12[C@]43[H]

InChI

1S/C20H20O6/c1-9-3-11-13(21)5-17-20(25-8-24-17)19(11)18(10(9)2)12-4-15-16(23-7-22-15)6-14(12)26-20/h4-6,9-11,18-19H,3,7-8H2,1-2H3/t9-,10+,11+,18+,19+,20+/m1/s1

InChI key

GMTJIWUFFXGFHH-WPAOEJHSSA-N

说明

Biochem/physiol Actions

Sauchinone is an anti-inflammatory and antioxidant lignan isolated from Saururus chinensis a medical plant used for the treatment of fever, jaundice, oedema and inflammatory disease in oriental folk medicine. Sauchinone inhibits LPS-inducible iNOS (NOS II), TNF-α and COX-2 expression in macrophages through suppression of IKBα phosphorylation. It appears that sauchinone protects against myocardial ischemia/reperfusion injury by inhibition of p28 phosphorylation.

Sauchinone is an anti-inflammatory and antioxidant.

Features and Benefits

This compound is featured on the Nitric Oxide Synthases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

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Sauchinone Protects Renal Mesangial Cell Dysfunction against Angiotensin II by Improving Renal Fibrosis and Inflammation.

Jung Joo Yoon et al.

International journal of molecular sciences, 21(19) (2020-09-27)

Abnormal and excessive growth of mesangial cells is important in the pathophysiologic processes of diabetes-associated interstitial fibrosis and glomerulosclerosis, leading to diabetic nephropathy, which eventually turns into end-stage renal disease. Sauchinone, a biologically-active lignan isolated from aerial parts of Saururus

全球贸易项目编号

货号	GTIN
SML0783-25MG	04061833223802
SML0783-5MG	04061833223819

主要文件

Sauchinone

≥98% (HPLC)

选择尺寸

关于此项目

Quality Level

assay

form

storage condition

color

solubility

shipped in

storage temp.

SMILES string

InChI

InChI key

Biochem/physiol Actions

Features and Benefits

Still not finding the right product?

安全信息

存储类别

wgk

flash_point_f

flash_point_c

法规信息

文件

分析证书(COA)

已有该产品？

技术文章和实验方案

商品

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