SML0804
(S)-CPP sodium salt
≥96% (HPLC)
别名:
(S)-2-Chloro-3-phenylpropanoic acid sodium salt, (aS)-a-chloro-benzenepropanoic acid sodium salt
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关于此项目
经验公式（希尔记法）:
C9H8ClO2 · Na
化学文摘社编号:
分子量:
206.60
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI key
HMHPCHNNVOLTFC-QRPNPIFTSA-M
SMILES string
[O-]C([C@@H](Cl)CC1=CC=CC=C1)=O.[Na+]
InChI
1S/C9H9ClO2.Na/c10-8(9(11)12)6-7-4-2-1-3-5-7;/h1-5,8H,6H2,(H,11,12);/q;+1/p-1/t8-;/m0./s1
assay
≥96% (HPLC)
form
powder
color
white to beige
solubility
H2O: 20 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase.
(S)-CPP is an inhibitor of branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, also know as BDK, or keto acid dehydrogenase kinase. BDK is a negative regulator of BCKDC activity. Inhibition of BDK by (S)-CPP (IC50 = 6.3 μM) leads to complex activation, and significant reduction of plasma levels of leucine/isoleucine and valine in wild type mice.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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