SML0815

YMU1

Name: YMU1
Brand: SIGMA

≥98% (HPLC)

别名:

4-[2-(4,6-Dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl]-1-piperazinecarboxylic acid ethyl ester, Ethyl 4-(2-(4,6-dimethyl-3-oxoisothiazolo[5,4-b]pyridin-2(3H)-yl)acetyl)piperazine-1-carboxylate

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关于此项目

经验公式（希尔记法）:

C₁₇H₂₂N₄O₄S

化学文摘社编号:

902589-96-2

分子量:

378.45

UNSPSC Code:

12352200

NACRES:

NA.77

主要文件

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SMILES string

[s]1[n]([c](c3c1nc(cc3C)C)=O)CC(=O)N2CCN(CC2)C(=O)OCC

InChI key

XXUFNNVFZFVKGP-UHFFFAOYSA-N

InChI

1S/C17H22N4O4S/c1-4-25-17(24)20-7-5-19(6-8-20)13(22)10-21-16(23)14-11(2)9-12(3)18-15(14)26-21/h9H,4-8,10H2,1-3H3

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 1 mg/mL, clear (warmed)

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

YMU1 is a cell-permeable and nontoxic inhibitor of hTMPK (thymidylate kinase) that sensitizes tumor cells to doxorubicin in vitro and in vivo.

YMU1 is a cell-permeable and nontoxic inhibitor of hTMPK (thymidylate kinase).

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.