SML0860
阿比朵尔 盐酸盐
≥98% (HPLC)
别名:
6-溴-4-((二甲氨基)甲基)-5-羟基-1-甲基-2-((苯硫基)甲基)-1H-吲哚-3-羧酸乙酯 单盐酸盐
产品名称
阿比朵尔 盐酸盐, ≥98% (HPLC)
SMILES string
S(Cc2[n](c3c(c(c(c(c3)Br)O)CN(C)C)c2C(=O)OCC)C)c1ccccc1.[Cl-].O.[H+]
InChI
1S/C22H25BrN2O3S.ClH.H2O/c1-5-28-22(27)20-18(13-29-14-9-7-6-8-10-14)25(4)17-11-16(23)21(26)15(19(17)20)12-24(2)3;;/h6-11,26H,5,12-13H2,1-4H3;1H;1H2
InChI key
PLWQHPWNKPKQJT-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
盐酸阿比多尔（ARB）是一种小分子单眼用化合物。用于预防流感病毒（IFV）诱导的重症肺炎和病毒相关细胞因子失调。ARB还具有一些免疫调节特性，包括干扰素诱导和巨噬细胞活化的作用。
阿比多尔是一种广谱抗病毒药，已证明对多种包膜和非包膜病毒具有活性，并在临床上用于治疗流感。阿比多尔抑制病毒进入宿主细胞并刺激免疫反应。阿比多尔抑制病毒衣壳与靶细胞的细胞膜之间的融合，从而防止病毒进入。
阿比多尔是一种抗流感抗病毒药。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
R A Abramovich et al.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 57(5-6), 3-6 (2012-11-20)
Rapid analysis of suppositories with ibuprofen and arbidol by quantitative 1H NMR spectroscopy was performed. Optimal conditions for the analysis were developed. The results are useful for design of rapid methods for quality control of suppositories with different components
Antiviral and anti-inflammatory activity of arbidol hydrochloride in influenza A (H1N1) virus infection.
Liu Q, et al.
Acta Pharmacologica Sinica, 34(8), 1075-1075 (2013)
Yaxin Sun et al.
International journal of clinical pharmacology and therapeutics, 51(5), 423-432 (2013-02-09)
Arbidol is licensed in Russia and China for prophylaxis and treatment of influenza A and B. This study was to assess the pharmacokinetics of single and multiple doses of arbidol in healthy Chinese volunteers. This was a single-center, open-label, two-phase
A A Romanovskaia et al.
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 54(5-6), 41-47 (2010-01-08)
Biological properties of influenza viruses A (H1N1), that were the cause of the infection in humans in April - May 2009, and the action of the Russian antivirals on their reproduction were studied in vitro. The nucleotide sequence in the
Ilenia Delogu et al.
Antiviral research, 90(3), 99-107 (2011-03-29)
Arbidol (ARB) is an antiviral drug originally licensed in Russia for use against influenza and other respiratory viral infections. Although a broad-spectrum antiviral activity has been reported for this drug, there is until now no data regarding its effects against
商品
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持