SML0866

BMS-191011

Name: BMS-191011
Brand: SIGMA

≥98% (HPLC)

别名:

3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one

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关于此项目

经验公式（希尔记法）:

C₁₆H₁₀ClF₃N₂O₃

化学文摘社编号:

202821-81-6

分子量:

370.71

UNSPSC Code:

12352200

NACRES:

NA.77

主要文件

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SMILES string

FC(F)(F)c1ccc(cc1)C2=NN(C(=O)O2)Cc3c(ccc(c3)Cl)O

InChI

1S/C16H10ClF3N2O3/c17-12-5-6-13(23)10(7-12)8-22-15(24)25-14(21-22)9-1-3-11(4-2-9)16(18,19)20/h1-7,23H,8H2

InChI key

QKOWACXSXTXRKA-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear (warmed)

storage temp.

room temp

Quality Level

100

Biochem/physiol Actions

BMS-191011 is a potent opener of BKCa opener (large-conductance Ca2+-activated K channel).

BMS-191011 is a potent opener of BKCa opener (large-conductance Ca2+-activated K channel). The compound BMS-191011 has neuroprotective properties in rodent models of stroke, and induces dialation of rat retinal arterioles.

Features and Benefits

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.