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SML0874

GMQ hydrochloride

Name: GMQ hydrochloride
Brand: SIGMA

≥95% (HPLC)

别名:

2-Guanidine-4-methylquinazoline hydrochloride, 4-Methyl-2-guanidino quinazoline hydrochloride, N-(4-Methyl-2-quinazolinyl)-guanidine hydrochloride, NSC 403387 hydrochloride

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关于此项目

经验公式（希尔记法）:

C₁₀H₁₁N₅ · HCl

化学文摘社编号:

5361-15-9

分子量:

237.69

NACRES:

NA.77

PubChem Substance ID:

329825612

UNSPSC Code:

12352200

MDL number:

MFCD00035249

Assay:

≥95% (HPLC)

Form:

powder

Storage condition:

desiccated

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属性

Quality Segment

100

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear (warmed)

storage temp.

room temp

SMILES string

CC1=NC(NC(N)=N)=NC2=C1C=CC=C2.Cl

InChI

1S/C10H11N5.ClH/c1-6-7-4-2-3-5-8(7)14-10(13-6)15-9(11)12;/h2-5H,1H3,(H4,11,12,13,14,15);1H

InChI key

VNPZWQRWOHFAPD-UHFFFAOYSA-N

说明

Biochem/physiol Actions

GMQ/2-guanidine-4-methylquinazoline is a potent and selective modulator of acid-sensing ion channel (ASIC).

GMQ/2-Guanidine-4-methylquinazoline is a potent and selective modulator of acid-sensing ion channel (ASIC) that activates ASIC3 channels under neutral pH. GQM blocks acid-induced maximal peak current and alters ASICs pH dependence for activation and inactivation.