SML0908
CCG-50014
≥98% (HPLC)
别名:
4-[(4-Fluorophenyl)methyl]-2-(4-methylphenyl)-1,2,4-thiadiazolidine-3,5-dione
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 5 mg/mL, clear (warmed)
储存温度
2-8°C
SMILES字符串
Fc1ccc(cc1)C[n]2[c]([s][n]([c]2=O)c3ccc(cc3)C)=O
InChI
1S/C16H13FN2O2S/c1-11-2-8-14(9-3-11)19-15(20)18(16(21)22-19)10-12-4-6-13(17)7-5-12/h2-9H,10H2,1H3
InChI key
QUIIIYITNGOFEI-UHFFFAOYSA-N
相关类别
生化/生理作用
CCG-50014 is an inhibitor of Regulators of G protein Signaling (RGS) proteins RGS4 and RGS8, which bind to the Gα -subunits of activated heterotrimeric G-proteins, and accelerate the rate of GTP hydrolysis, acting as GTPase activating proteins. CCG-50014 irreversibly binds and destabilizes RGS proteins with no affect on Gα0, while blocking GTPase activity and Gα0-dependent translocation of RGS4 to the membrane.
CCG-50014 is an inhibitor of Regulators of G protein Signaling (RGS) proteins RGS4 and RGS8.
特点和优势
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
商品
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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