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Merck
CN

SML0915

Xipamide

≥98% (HPLC)

别名:

5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide, BE 1293, BEI 1293, MJF 10938

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关于此项目

经验公式(希尔记法):
C15H15ClN2O4S
化学文摘社编号:
分子量:
354.81
UNSPSC Code:
12352200
EC Number:
238-216-4
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
Storage condition:
desiccated
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Quality Level

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

[S](=O)(=O)(N)c1c(cc(c(c1)C(=O)Nc2c(cccc2C)C)O)Cl

InChI

1S/C15H15ClN2O4S/c1-8-4-3-5-9(2)14(8)18-15(20)10-6-13(23(17,21)22)11(16)7-12(10)19/h3-7,19H,1-2H3,(H,18,20)(H2,17,21,22)

InChI key

MTZBBNMLMNBNJL-UHFFFAOYSA-N

Biochem/physiol Actions

Xipamide is a sulfonamide diuretic that blocks sodium reabsorption in the distal tubules of the kidney, resulting in increased urine output. Xiopamide also blocks the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel.
Xipamide is a sulfonamide diuretic.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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[What did the ALLHAT study bring? To do the one without foregoing the other].
MMW Fortschritte der Medizin, 145(51-52), 36-37 (2004-02-21)
[Thiazide analogs. Also can be used in renal failure].
MMW Fortschritte der Medizin, 145(33-34), 57-57 (2003-10-07)
[Proven in the practice. Follow up of the use confirms high trial value].
MMW Fortschritte der Medizin, 145(51-52), 37-37 (2004-02-21)
F Soria et al.
Revista espanola de cardiologia, 44(6), 389-394 (1991-06-01)
With the objective of trying to prove the regression of ventricular mass in patients with essential hypertension, with and without left ventricular hypertrophy (LVH), we studied 42 patients of both sexes with echocardiography, measuring the left ventricular mass (LVM), the
Ahmed S Al-Kady
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 97, 284-289 (2012-07-10)
A simple, selective and sensitive spectrophotometric method for the determination of trace amounts of Zr(IV) in aqueous samples was performed, based on complexation reaction between Zr(IV) and 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide (xipamide). The important analytical parameters and their effects on the reported system

全球贸易项目编号

货号GTIN
SML0915-50MG04061832576671
SML0915-10MG04061835374977

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