SML0915
Xipamide
≥98% (HPLC)
别名:
5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide, BE 1293, BEI 1293, MJF 10938
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
DMSO: 20 mg/mL, clear
储存温度
−20°C
SMILES字符串
[S](=O)(=O)(N)c1c(cc(c(c1)C(=O)Nc2c(cccc2C)C)O)Cl
InChI
1S/C15H15ClN2O4S/c1-8-4-3-5-9(2)14(8)18-15(20)10-6-13(23(17,21)22)11(16)7-12(10)19/h3-7,19H,1-2H3,(H,18,20)(H2,17,21,22)
InChI key
MTZBBNMLMNBNJL-UHFFFAOYSA-N
相关类别
生化/生理作用
Xipamide is a sulfonamide diuretic that blocks sodium reabsorption in the distal tubules of the kidney, resulting in increased urine output. Xiopamide also blocks the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel.
Xipamide is a sulfonamide diuretic.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
F Soria et al.
Revista espanola de cardiologia, 44(6), 389-394 (1991-06-01)
With the objective of trying to prove the regression of ventricular mass in patients with essential hypertension, with and without left ventricular hypertrophy (LVH), we studied 42 patients of both sexes with echocardiography, measuring the left ventricular mass (LVM), the
[What did the ALLHAT study bring? To do the one without foregoing the other].
MMW Fortschritte der Medizin, 145(51-52), 36-37 (2004-02-21)
[Thiazide analogs. Also can be used in renal failure].
MMW Fortschritte der Medizin, 145(33-34), 57-57 (2003-10-07)
[Proven in the practice. Follow up of the use confirms high trial value].
MMW Fortschritte der Medizin, 145(51-52), 37-37 (2004-02-21)
P Lijnen et al.
Cardiovascular drugs and therapy, 5(4), 741-746 (1991-08-01)
The effect of xipamide on plasma alpha-atrial natriuretic peptide and the renin-aldosterone-kallikrein system have been studied in 12 healthy men, using a double-blind cross-over design. After a run-in period on placebo of 1 week, the subjects were treated with either
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