SML0931
卡比马唑
≥98% (HPLC)
别名:
1-Ethoxycarbonyl-3-methyl-2-thio-4-imidazoline, 1-Methyl-3-carbethoxy-2-thioglyoxalone, 2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1-carboxylic acid ethyl ester, Athyromazole, Carbethoxymethimazole, Carbimazol, Ethyl 3-methyl-2-thioimidazoline-1-carboxylate
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关于此项目
经验公式（希尔记法）:
C7H10N2O2S
化学文摘社编号:
分子量:
186.23
UNSPSC Code:
12352200
EC Number:
244-854-4
NACRES:
NA.77
产品名称
卡比马唑, ≥98% (HPLC)
SMILES string
S=[c]1[n](cc[n]1C(=O)OCC)C
InChI key
CFOYWRHIYXMDOT-UHFFFAOYSA-N
InChI
1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
Quality Level
相关类别
Biochem/physiol Actions
Carbimazole is a pro-drug of methimazole that is an inhibitor of thyroid enzyme thyroperoxidase.
Carbimazole is a pro-drug of methimazole that is an inhibitor of thyroid enzyme thyroperoxidase. Carbimazole is used to treat hyperthyroidism. Also, carbimazole induces phosphorylation of eukaryotic elongation factor eEF2.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Adoree Yi Ying Lim et al.
Singapore medical journal, 54(7), e133-e136 (2013-08-01)
A 24-year-old Chinese woman with Graves' disease presented with myositis two months after treatment with carbimazole. The patient's myositis resolved with hydration and cessation of carbimazole. No other causes of myositis were found, and a change in the medication to
Franz Ludwig Dumoulin et al.
BMJ case reports, 2012, doi:10-doi:10 (2012-05-19)
A middle aged woman, previously healthy with the exception of mild seasonal asthma was presented with signs of acute hepatitis. The further investigation showed acute hepatitis E virus infection associated with autoimmune thyroiditis. Treatment was started with propranolol and carbimazol
Iodinated contrast-induced thyrotoxicosis.
Paul Dunne et al.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 185(2), 144-147 (2012-11-14)
E T Bell et al.
The Journal of small animal practice, 53(11), 661-663 (2012-09-11)
A 12-year-old female neutered ragdoll crossbred cat was presented for investigation of generalised weakness and regurgitation. The cat was being treated with transdermal methimazole for hyper-thyroidism, which had been diagnosed 10 weeks previously. An acetylcholine receptor antibody titre was consistent
Dinesh Kumar Dhanwal et al.
The Journal of the Association of Physicians of India, 59, 561-562 (2012-02-18)
Hyperthyroidism is associated with bone loss, which is reversible after treatment. The extent of reversibility of loss of bone mass density (BMD) in hyperthyroid patients after treatment especially at forearm is not clear. Therefore, the present study was conducted to
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