SML0931
卡比马唑
≥98% (HPLC)
别名:
1-Ethoxycarbonyl-3-methyl-2-thio-4-imidazoline, 1-Methyl-3-carbethoxy-2-thioglyoxalone, 2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1-carboxylic acid ethyl ester, Athyromazole, Carbethoxymethimazole, Carbimazol, Ethyl 3-methyl-2-thioimidazoline-1-carboxylate
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 5 mg/mL, clear (warmed)
储存温度
2-8°C
SMILES字符串
S=[c]1[n](cc[n]1C(=O)OCC)C
InChI
1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3
InChI key
CFOYWRHIYXMDOT-UHFFFAOYSA-N
相关类别
生化/生理作用
Carbimazole is a pro-drug of methimazole that is an inhibitor of thyroid enzyme thyroperoxidase.
Carbimazole is a pro-drug of methimazole that is an inhibitor of thyroid enzyme thyroperoxidase. Carbimazole is used to treat hyperthyroidism. Also, carbimazole induces phosphorylation of eukaryotic elongation factor eEF2.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Dhanya Muralidharan et al.
Oral surgery, oral medicine, oral pathology and oral radiology, 115(5), 617-623 (2013-03-05)
Animal studies have shown thyroid dysfunction affects salivary gland functioning, however conclusive human studies are lacking. We sought to assess the qualitative and quantitative changes in saliva among subjects with thyroid dysfunction prior to and following treatment. A longitudinal observational
Which antithyroid drug regimen in paediatric Graves' disease?
Daniel Schenk et al.
Clinical endocrinology, 77(6), 806-807 (2012-07-24)
Sarah M A Caney
Journal of feline medicine and surgery, 15(6), 494-502 (2013-04-18)
Hyperthyroidism is the most common feline endocrinopathy. Treatment options comprise anti-thyroid medication, iodine-restricted diet, surgical thyroidectomy and radioiodine. One hundred and eleven owners of hyperthyroid cats completed a detailed survey asking about their experiences and views on the management of
Nishikant Damle et al.
Journal of pediatric endocrinology & metabolism : JPEM, 24(11-12), 1051-1054 (2012-02-09)
Autonomously functioning thyroid nodules (AFTN) are extremely rare in children. Malignancy may be rarely found in hyperfunctioning 'hot' nodules in adults. However, there are limited reports of AFTNs in young children presenting as or developing malignancy in future. We report
Dinesh Kumar Dhanwal et al.
The Journal of the Association of Physicians of India, 59, 561-562 (2012-02-18)
Hyperthyroidism is associated with bone loss, which is reversible after treatment. The extent of reversibility of loss of bone mass density (BMD) in hyperthyroid patients after treatment especially at forearm is not clear. Therefore, the present study was conducted to
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