SML0931
卡比马唑
≥98% (HPLC)
别名:
1-Ethoxycarbonyl-3-methyl-2-thio-4-imidazoline, 1-Methyl-3-carbethoxy-2-thioglyoxalone, 2,3-Dihydro-3-methyl-2-thioxo-1H-imidazole-1-carboxylic acid ethyl ester, Athyromazole, Carbethoxymethimazole, Carbimazol, Ethyl 3-methyl-2-thioimidazoline-1-carboxylate
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关于此项目
经验公式（希尔记法）:
C7H10N2O2S
化学文摘社编号:
分子量:
186.23
UNSPSC Code:
12352200
EC Number:
244-854-4
NACRES:
NA.77
产品名称
卡比马唑, ≥98% (HPLC)
SMILES string
S=[c]1[n](cc[n]1C(=O)OCC)C
InChI key
CFOYWRHIYXMDOT-UHFFFAOYSA-N
InChI
1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
Quality Level
相关类别
Biochem/physiol Actions
Carbimazole is a pro-drug of methimazole that is an inhibitor of thyroid enzyme thyroperoxidase.
Carbimazole is a pro-drug of methimazole that is an inhibitor of thyroid enzyme thyroperoxidase. Carbimazole is used to treat hyperthyroidism. Also, carbimazole induces phosphorylation of eukaryotic elongation factor eEF2.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Which antithyroid drug regimen in paediatric Graves' disease?
Daniel Schenk et al.
Clinical endocrinology, 77(6), 806-807 (2012-07-24)
Nishikant Damle et al.
Journal of pediatric endocrinology & metabolism : JPEM, 24(11-12), 1051-1054 (2012-02-09)
Autonomously functioning thyroid nodules (AFTN) are extremely rare in children. Malignancy may be rarely found in hyperfunctioning 'hot' nodules in adults. However, there are limited reports of AFTNs in young children presenting as or developing malignancy in future. We report
Dhanya Muralidharan et al.
Oral surgery, oral medicine, oral pathology and oral radiology, 115(5), 617-623 (2013-03-05)
Animal studies have shown thyroid dysfunction affects salivary gland functioning, however conclusive human studies are lacking. We sought to assess the qualitative and quantitative changes in saliva among subjects with thyroid dysfunction prior to and following treatment. A longitudinal observational
Dinesh Kumar Dhanwal et al.
The Journal of the Association of Physicians of India, 59, 561-562 (2012-02-18)
Hyperthyroidism is associated with bone loss, which is reversible after treatment. The extent of reversibility of loss of bone mass density (BMD) in hyperthyroid patients after treatment especially at forearm is not clear. Therefore, the present study was conducted to
Pinaki Dutta et al.
The Indian journal of medical research, 136(2), 242-248 (2012-09-11)
Hyperthyroidism is associated with increased food intake, energy expenditure and altered body composition. This study was aimed to evaluate the role of adipocytokines in weight homeostasis in patients with hyperthyroidism. Patients (n=27, 11men) with hyperthyroidism (20 Graves' disease, 7 toxic
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