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Merck
CN

SML0934

Sigma-Aldrich

Enfuvirtide acetate salt

≥95% (HPLC), HIV fusion inhibitor , powder

别名:

T-20 acetate salt

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关于此项目

经验公式(希尔记法):
C204H301N51O64 · xC2H4O2
化学文摘社编号:
分子量:
4491.88 (free base basis)
UNSPSC代码:
51111800
NACRES:
NA.77
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产品名称

Enfuvirtide acetate salt, ≥95% (HPLC)

质量水平

方案

≥95% (HPLC)

表单

powder

储存条件

desiccated
protect from light

颜色

white to off-white

运输

wet ice

储存温度

−20°C

Amino Acid Sequence

Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu- Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu- Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu- Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2 acetate

一般描述

Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus. Enfuvirtide is catabolized with the help of proteolytic enzymes.

生化/生理作用

Enfuvirtide is an HIV fusion inhibitor used to patients with multi-drug resistant HIV. Enfuvirtide binds to gp41 preventing the creation of an entry pore for the HIV-1 virus.
Enfuvirtide is an HIV fusion inhibitor.

其他说明

Light sensitive

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Desk Encyclopedia of Microbiology (2010)
Alexander Herrmann et al.
Scientific reports, 10(1), 1326-1326 (2020-01-30)
Overcoming the global health threat of HIV infection requires continuous pipelines of novel drug candidates. We identified the γ-pyrone polyketides Aureothin/Neoaureothin as potent hits by anti-HIV screening of an extensive natural compound collection. Total synthesis of a structurally diverse group

商品

Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.

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