生化/生理作用
ML291 specifically activates the apoptotic arm of the cellular unfolded protein response ( UPR) EC50 = 762 nM) with 105-fold selectivity over activation of the adaptive UPR pathway. ML291 induces apoptosis in wild-type mouse embryonic fibroblasts (MEFs), but not in CHOP KO MEFs.
ML291 specifically activates the apoptotic arm of the cellular unfolded protein response.
特点和优势
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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