SML0979
Bantag-1 三氟乙酸盐
≥95% (HPLC)
别名:
Boc-Phe-His-4-氨基-5-环己基-2,4,5-三苯氧基戊烯基-Leu-（3-二甲基氨基）苄酰胺N-甲基铵 三氟乙酸盐
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关于此项目
经验公式（希尔记法）:
C48H73N8O7 · xC2HF3O2
分子量:
874.14 (free base basis)
NACRES:
NA.77
UNSPSC Code:
12352200
产品名称
Bantag-1 三氟乙酸盐, ≥95% (HPLC)
assay
≥95% (HPLC)
form
powder
color
white to off-white
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Bantag-1 是孤儿 GPCR 铃蟾肽受体亚型 3（BRS-3）的高特异性、高亲和力的拮抗剂。
Bantag-1 是孤儿 GPCR 铃蟾肽受体亚型 3（BRS-3）的高特异性、高亲和力的拮抗剂。 Bantag-1 在 BRS-3 表达细胞中的结合亲和力为 1.3 nM。
General description
Bantag-1 是一种肽拮抗剂。溶于水溶液。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Molecular basis for high affinity and selectivity of peptide antagonist, Bantag-1, for the orphan BB3 receptor.
Nakamura T, et al.
Biochemical Pharmacology, 115, 64-76 (2016)
Xiao-Ming Guan et al.
Cell metabolism, 11(2), 101-112 (2010-01-26)
Bombesin receptor subtype 3 (BRS-3) is a G protein coupled receptor whose natural ligand is unknown. We developed potent, selective agonist (Bag-1, Bag-2) and antagonist (Bantag-1) ligands to explore BRS-3 function. BRS-3-binding sites were identified in the hypothalamus, caudal brainstem
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