SMILES string
ClC1=C(C(=O)N(C1=O)CC(CN2C(=O)C(=C(C2=O)Cl)Cl)(C)C)Cl
InChI
1S/C13H10Cl4N2O4/c1-13(2,3-18-9(20)5(14)6(15)10(18)21)4-19-11(22)7(16)8(17)12(19)23/h3-4H2,1-2H3
InChI key
PCOXPBOKDABARQ-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to light brown
solubility
DMSO: 3 mg/mL, clear (warmed)
storage temp.
2-8°C
Quality Level
相关类别
Biochem/physiol Actions
NSC 617145具有230nM的IC50值。
NSC 617145是Werner综合征解旋酶(WRN)的一种有效的细胞渗透性抑制剂。
NSC 617145是Werner综合征解旋酶(WRN)的一种有效的细胞渗透性抑制剂,能够引起癌细胞中双链断裂(DSB)的积累和染色体异常。
Features and Benefits
该化合物是基因调控研究推荐产品。点击此处 ,查看更多基因调控精选产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息,请访问 sigma.com/discover-bsm。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
DNA repair in cancer therapy, 257-257 (2011)
商品
We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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