SML1041
Atreleuton
≥98% (HPLC)
别名:
(R)-N-(3-(5-(4-Fluorophenylmethyl)thien-2-yl)-1-methyl-2-propynyl)-N-hydroxyurea, A8576, ABT 761, VIA-2291
SMILES string
Fc1ccc(cc1)Cc2[s]c(cc2)C#C[C@H](N(O)C(=O)N)C
InChI
1S/C16H15FN2O2S/c1-11(19(21)16(18)20)2-7-14-8-9-15(22-14)10-12-3-5-13(17)6-4-12/h3-6,8-9,11,21H,10H2,1H3,(H2,18,20)/t11-/m1/s1
InChI key
MMSNEKOTSJRTRI-LLVKDONJSA-N
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D +40 to +50°, c = 1 in methanol
color
white to beige
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Atreleuton is a reversible 5-lipoxygenase inhibitor.
Atreleuton is a reversible 5-lipoxygenase inhibitor. Atreleuton exhibits potent and selective inhibition of leukotriene formation both in vitro and in vivo.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
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