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Merck
CN

SML1044

Sigma-Aldrich

佐奎达 盐酸盐

≥98% (HPLC), powder, p-Glycoprotein inhibitor

别名:

LY-335979, RS-33295-198, （2R）-抗-5- [3- [4-（10,11-二氟亚甲基二苯并亚苄基-5-基）哌嗪-1-基] -2-羟基丙氧基]喹啉 盐酸盐

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关于此项目

经验公式（希尔记法）:
C32H31F2N3O2 · xHCl
化学文摘社编号:
167354-41-8
分子量:
527.60 (free base basis)
UNSPSC代码:
12161501
PubChem化学物质编号:
329825638
NACRES:
NA.77

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产品名称

佐奎达 盐酸盐, ≥98% (HPLC)

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to beige

溶解性

H2O: 4 mg/mL, clear (warmed)

储存温度

−20°C

SMILES字符串

O[C@@H](COC1=C(C=CC=N2)C2=CC=C1)CN(CC3)CCN3[C@@H]4C5=C(C=CC=C5)[C@@H]6[C@@H](C6(F)F)C7=C4C=CC=C7.Cl

InChI

1S/C32H31F2N3O2.ClH/c33-32(34)29-22-7-1-3-9-24(22)31(25-10-4-2-8-23(25)30(29)32)37-17-15-36(16-18-37)19-21(38)20-39-28-13-5-12-27-26(28)11-6-14-35-27;/h1-14,21,29-31,38H,15-20H2;1H/t21-,29-,30+,31-;/m1./s1

InChI key

VQJFFWJUYDGTQZ-FCNWNIDBSA-N

相关类别

生化/生理作用

Zosuqidar是一种P-糖蛋白（P-gp，MDR1）的有效抑制剂，P-糖蛋白是一种转运蛋白，是细胞药物外排的一种关键调节剂。
Zosuqidar是一种P-糖蛋白（P-gp，MDR1）的有效抑制剂，P-糖蛋白是一种转运蛋白，是细胞药物外排的一种关键调节剂。 Zosuquidar可使AML和其他癌细胞系对细胞毒性药物敏感。

特点和优势

该化合物是ADME Tox研究推荐产品。点击此处 ，查看更多ADME Tox精选产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息，请访问 sigma.com/discover-bsm。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H315,H319,H335

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000463901
0000463901
0000429817
0000429817
0000220155

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