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SML1050

DC260126

≥98% (HPLC)

别名:

N-(4-Butylphenyl)-4-fluoro-benzenesulfonamide

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关于此项目

经验公式（希尔记法）:
C16H18FNO2S
化学文摘社编号:
346692-04-4
分子量:
307.38
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

Fc1ccc(cc1)[S](=O)(=O)Nc2ccc(cc2)CCCC

InChI

1S/C16H18FNO2S/c1-2-3-4-13-5-9-15(10-6-13)18-21(19,20)16-11-7-14(17)8-12-16/h5-12,18H,2-4H2,1H3

InChI key

CNGHPXKWPGIDSK-UHFFFAOYSA-N

Biochem/physiol Actions

DC260126 is a FFA1 (GPR40) selective antagonist.
DC260126 is a FFA1 (GPR40) selective antagonist. In FFA1-expressing CHO cells, DC260126 blocks linoleic acid-induced Ca2+ elevation and ERK phosphorylation (IC50 = 6028 μM), as well as palmitic acid potentiated glucose-stimulated insulin secretion. The compound DC260126 blocks MIN6 β cells from palmitic acid-induced ER stress and apoptosis.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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