SML1136
SW155246
≥98% (HPLC)
别名:
4-Chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide
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关于此项目
经验公式（希尔记法）:
C16H11ClN2O5S
化学文摘社编号:
分子量:
378.79
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
protect from light
assay
≥98% (HPLC)
form
powder
storage condition
protect from light
color
white to light brown
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
SMILES string
OC1=CC=C(NS(=O)(C2=CC=C(Cl)C([N+]([O-])=O)=C2)=O)C3=C1C=CC=C3
InChI
1S/C16H11ClN2O5S/c17-13-6-5-10(9-15(13)19(21)22)25(23,24)18-14-7-8-16(20)12-4-2-1-3-11(12)14/h1-9,18,20H
InChI key
JDYDEJYIVZNWQU-UHFFFAOYSA-N
Biochem/physiol Actions
SW155246 is a potent and selective DNMT1 (DNA methyltransferase 1) inhibitor that demethylates cytosines in vivo in a cell-based assay without affecting protein levels or generating reactive oxygen species. SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells.
SW155246 is a potent and selective DNMT1 (DNA methyltransferase 1) inhibitor.
Features and Benefits
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Other Notes
light sensitive
警示词
Warning
危险代码
预防性声明
Hazard Classifications
Eye Irrit. 2
存储类别
13 - Non Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable