SML1205

BVT.2733

Name: BVT.2733
Brand: SIGMA

≥98% (HPLC)

别名:

1-[[2-[[(3-Chloro-2-methylphenyl)sulfonyl]amino]-4-thiazolyl]acetyl]-4-methyl-piperazine, 3-Chloro-2-methyl-N-[4-[2-(4-methyl-1-piperazinyl)-2-oxoethyl]-2-thiazolyl]-benzenesulfonamide, BVT 2733

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关于此项目

经验公式（希尔记法）:

C₁₇H₂₁ClN₄O₃S₂

化学文摘社编号:

376640-41-4

分子量:

428.96

NACRES:

NA.77

PubChem Substance ID:

329825717

UNSPSC Code:

51111800

MDL number:

MFCD13152134

主要文件

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InChI

1S/C17H21ClN4O3S2/c1-12-14(18)4-3-5-15(12)27(24,25)20-17-19-13(11-26-17)10-16(23)22-8-6-21(2)7-9-22/h3-5,11H,6-10H2,1-2H3,(H,19,20)

SMILES string

O=S(C1=C(C)C(Cl)=CC=C1)(NC2=NC(CC(N3CCN(C)CC3)=O)=CS2)=O

InChI key

YDPRNGAPPNPYQQ-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

BVT.2733 is a potent and selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) that protects osteoblasts against endogenous glucocorticoid induced dysfunction. BVT.2733 lowers blood glucose levels in in hyperglycaemic mice.

BVT.2733 is a potent and selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1).