SML1234
HAMNO
≥98% (HPLC)
别名:
(1Z)-1-[(2-Hydroxyanilino)methylidene]naphthalen-2-one, 1-[[(2-Hydroxyphenyl)imino]methyl]-2-naphthalenol, CID 6335338, MLS000737724, NS C111847, NSC111847
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
yellow to orange
溶解性
DMSO: 10 mg/mL, clear
储存温度
2-8°C
SMILES字符串
N(c3c(cccc3)O)\C=C1\c2c(cccc2)C=CC\1=O
InChI key
NADCEWZYITXLKJ-KAMYIIQDSA-N
相关类别
生化/生理作用
HAMNO is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response. HAMNO binds the N-terminal domain of RPA70 and inhibits both ATR autophosphorylation and phosphorylation of RPA32 Ser33 by ATR. HAMNO enhances DNA replication stress in cancer cells and slow tumor growth in vivo.
HAMNO is a potent and selective inhibitor of replication protein A (RPA) interactions.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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