SML1302
Nap-FF
≥98% (HPLC)
别名:
(S)-2-[(S)-2-[2-(Naphthalen-6-yl)acetamido]-3-phenylpropanamido]-3-phenylpropanoic acid, 2-Naa-FF, N-[2-(2-Naphthalenyl)acetyl]-L-phenylalanyl-L-phenylalanine
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关于此项目
经验公式（希尔记法）:
C30H28N2O4
化学文摘社编号:
分子量:
480.55
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)CC3=CC4=CC=CC=C4C=C3
InChI
1S/C30H28N2O4/c33-28(20-23-15-16-24-13-7-8-14-25(24)17-23)31-26(18-21-9-3-1-4-10-21)29(34)32-27(30(35)36)19-22-11-5-2-6-12-22/h1-17,26-27H,18-20H2,(H,31,33)(H,32,34)(H,35,36)/t26-,27-/m0/s1
InChI key
IYVWBKAVHZILOI-SVBPBHIXSA-N
Biochem/physiol Actions
Nap-FF (2-Naa-FF) is a cell penetrant dipeptide that self-assembly and adopt the β-sheet structures to form prion-like nanofibrils of small molecules (PriSM). PriSM of Nap-FF are selectively cytotoxic to gliomas cancer cells in a presence of stromal cells. PriSM of Nap-FF selectively accumulate in cancer cells, impedes the dynamics of cytoskeletal filaments, and induces apoptosis.
Nap-FF is a cell penetrant dipeptide.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable