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Merck
CN

SML1325

HS-72

≥98% (HPLC)

别名:

(S)-N-(1-propyl-1H-benzimidazol-2-yl)-1-(2-pyrazinyl)-3-Piperidinecarboxamide

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关于此项目

经验公式(希尔记法):
C20H24N6O
分子量:
364.44
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

Biochem/physiol Actions

HS-72 is also termed as ((S)-N-(1-propyl-1H-benzo[d]imidazol-2-yl)-1-(pyrazin-2-yl)piperidine-3-carboxamide). It is considered as a powerful anti-dengue virus (DENV) therapeutic agent. It displays anti-DENV activity in monocyte and liver cell lines. HS-72 stimulates the accumulation of cellular proteins.
HS-72 is a cell permeable, highly selective allosteric inhibitor of inducible Hsp70 (Hsp70i) over constitutively active Hsc70. HS-72 inhibits cancer cell proliferation and promotes a survival in a HER2+ mouse model of breast cancer.
HS-72 is a cell permeable, highly selective allosteric inhibitor of inducible Hsp70 (Hsp70i).


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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