SML1349
SB-207266
≥98% (HPLC)
别名:
1′-Butyl-4′-piperidinylmethyl ester, 8-Amino-7-chloro-2,3-dihydro-1,4-benzodioxan-5-carboxylic acid, N-1-Butyl-4-piperinylmethyl)-3,4-dihydro-2H-[1,3] oxazino[3,2-a]indole-10-carboxamide, Piboserod
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关于此项目
经验公式（希尔记法）:
C22H31N3O2
化学文摘社编号:
分子量:
369.50
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI key
KVCSJPATKXABRQ-UHFFFAOYSA-N
SMILES string
O=C(NCC1CCN(CCCC)CC1)C2=C3N(CCCO3)C4=C2C=CC=C4
InChI
1S/C22H31N3O2/c1-2-3-11-24-13-9-17(10-14-24)16-23-21(26)20-18-7-4-5-8-19(18)25-12-6-15-27-22(20)25/h4-5,7-8,17H,2-3,6,9-16H2,1H3,(H,23,26)
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
SB-207266 is a Serotonin 5-HT4 receptor antagonist in vivo.
SB-207266 is a potent, selective, orally active and long-acting 5-HT4 antagonist in vivo.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Barbora Waclawiková et al.
PLoS biology, 19(1), e3001070-e3001070 (2021-01-23)
Microbial conversion of dietary or drug substrates into small bioactive molecules represents a regulatory mechanism by which the gut microbiota alters intestinal physiology. Here, we show that a wide variety of gut bacteria can metabolize the dietary supplement and antidepressant
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