SML1420
FSL-1
≥80% (HPLC), Toll-like Receptor 2/6 agonist, powder
别名:
(R,S)-Pam2Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH, Fibroblast-stimulating Lipopeptide, Pam2CGDPKHPKSF, S-[2,3-Bis[(1-Oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-a-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine
产品名称
FSL-1, ≥80% (HPLC)
assay
≥80% (HPLC)
form
powder
color
white to off-white
solubility
H2O: soluble
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF-KB.
FSL-1 (Pam2CGDPKHPKSF) is a synthetic lipoprotein that acts as a Toll-like Receptor 2/6 (TLR2/6) agonist and activator of nuclear transcription factor NF-KB. FSL-1 is based on the N-terminal part of the 44-kDa lipoprotein LP44 of Mycoplasma salivarium. FSL-1 showed higher stimulatory activity than MALP-2 in its ability to induce TNF-α production in macrophages and NF-κB in TLR2/TLR6 transfected HEK293 cells.
FSL-1 is a bacterial-derived toll-like receptor 2/6 agonist. It is capable of increasing resistance to herpes simplex virus type 2 (HSV-2) infection.
Other Notes
Air sensitive
Preparation Note
Reconstitute in endotoxin-free water.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
FSL-1, a bacterial-derived toll-like receptor 2/6 agonist, enhances resistance to experimental HSV-2 infection
Rose WA, et al.
Virology Journal, 6, 195-195 (2009)
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