SML1424
Ac-YVAD-pNA
≥98% (HPLC)
别名:
Caspase-1 substrate (Chromogenic), N-α-acetyl-Tyr-Val-Ala-Asp-p-nitroanilide, N-acetyl-L-tyrosyl-L-valyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine
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选择尺寸
关于此项目
经验公式（希尔记法）:
C29H36N6O10
化学文摘社编号:
分子量:
628.63
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
Ac-YVAD-pNA, ≥98% (HPLC)
InChI
1S/C29H36N6O10/c1-15(2)25(34-28(42)22(31-17(4)36)13-18-5-11-21(37)12-6-18)29(43)30-16(3)26(40)33-23(14-24(38)39)27(41)32-19-7-9-20(10-8-19)35(44)45/h5-12,15-16,22-23,25,37H,13-14H2,1-4H3,(H,30,43)(H,31,36)(H,32,41)(H,33,40)(H,34,42)(H,38,39)/t16-,22-,23-,25-/m0/s1
SMILES string
O=C([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CC1=CC=C(O)C=C1)=O)=O)=O)NC2=CC=C([N+]([O-])=O)C=C2
InChI key
YDPNOCSPPGFBPX-XNHCRPTKSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Ac-YVAD-pNA is a chromogenic selective caspase-1 substrate
Ac-YVAD-pNA is a very selective chromogenic substrate for caspase-1, a key mediator of inflammatory processes formerly known as interleukin (IL)-1-converting enzyme. Ac-YVAD-pNA is used to determine caspase-1 activity. Cleavage of Ac-YVAD-pNA by caspase-1 releases pNA (p-nitroanilide), which can be quantified spectrophotometrically at 405 nm.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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