InChI key
DURULFYMVIFBIR-UHFFFAOYSA-N
InChI
1S/C14H22N2O3/c1-10(2)15-8-13(18)9-19-14-6-4-12(5-7-14)16-11(3)17/h4-7,10,13,15,18H,8-9H2,1-3H3,(H,16,17)
SMILES string
CC(NC1=CC=C(OCC(O)CNC(C)C)C=C1)=O
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 15 mg/mL, clear
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
普拉洛尔是一种有效且选择性的β-肾上腺素受体拮抗剂。
普拉洛尔是一种有效且选择性的β-肾上腺素受体拮抗剂。 普拉洛尔是一种β受体阻滞剂,由于其不良反应(干燥性角膜结膜炎、结膜瘢痕、纤维化、化生和萎缩)而停止使用。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Jian-Qiao Cheng et al.
Molecules (Basel, Switzerland), 24(4) (2019-03-03)
This paper presents an application of high performance liquid chromatography coupled with quadrupole orbitrap high-resolution mass spectrometry (HPLC-Q-Orbitrap HRMS) for the analysis of 27 β-blockers and metabolites in milk powder. Homogenized milk power samples were extracted by acetonitrile and purified
Guohua Huang et al.
Combinatorial chemistry & high throughput screening, 19(2), 121-128 (2015-11-11)
It is crucial to identify the molecular targets of a compound during the course of the new drug discovery and drug development. Due to the complexity of biological systems, finding drug targets by biological experiments is very tedious and expensive.
Gerrit Müller et al.
Autophagy, 16(8), 1380-1395 (2019-11-02)
Oxidative stress and Th17 cytokines are important mediators of inflammation. Treatment with beta-adrenoceptor (ADRB) antagonists (beta-blockers) is associated with induction or aggravation of psoriasis-like skin inflammation, yet the underlying mechanisms are poorly understood. Herein, we identify lysosomotropic beta-blockers as critical
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