SML1498
Cinepazide maleate
≥98% (HPLC)
别名:
(E)-1-[4-(2-Oxo-2-pyrrolidin-1-ylethyl)piperazin-1-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one maleate, 1-(Pyrrolidinyl-1-carbonyl)-methyl-4-(3,4,5-trimethoxycinnamoyl)-piperazine-maleate
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关于此项目
经验公式（希尔记法）:
C22H31N3O5 · C4H4O4
化学文摘社编号:
分子量:
533.57
MDL编号:
UNSPSC代码:
12352125
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
H2O: 20 mg/mL, clear
储存温度
2-8°C
SMILES字符串
O=C(O)/C=C\C(O)=O.O=C(N1CCN(CC(N2CCCC2)=O)CC1)/C=C/C3=CC(OC)=C(OC)C(OC)=C3
InChI
1S/C22H31N3O5.C4H4O4/c1-28-18-14-17(15-19(29-2)22(18)30-3)6-7-20(26)25-12-10-23(11-13-25)16-21(27)24-8-4-5-9-24;5-3(6)1-2-4(7)8/h6-7,14-15H,4-5,8-13,16H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b7-6+;2-1-
InChI key
XSTJTOKYCAJVMJ-GVTSEVKNSA-N
一般描述
Cinepazide maleate can be synthesized from ethyl chlorocarbonate activation and (E) 3,4,5-trimethoxycinnamylic acid.
生化/生理作用
Cinepazide maleate is a vasodilator used clinically in China used for the treatment of cardiovascular and cerebrovascular diseases, and peripheral vascular diseases.
Cinepazide maleate is a vasodilator used clinically in China used in China for the treatment of cardiovascular and cerebrovascular diseases, and peripheral vascular diseases. Cinepazide maleate is thought to act as a potentiator of adenosine A2 receptors and has also been characterized as a calcium channel blocker. It was withdrawn for agranulocytosis in several countries.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
An Improved Synthesis of Cinepazide Maleate.
LIU, Hua-xiang, et al.
Fine Chemicals / ????, 10, 012-012 (2009)
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