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SML1500

Spadin trifluoroacetate salt

≥95% (HPLC)

别名:

L-Tyrosyl-L-alanyl-L-prolyl-L-leucyl-L-prolyl-L-arginyl-L-tryptophyl-L-serylglycyl-L-prolyl-L-isoleucylglycyl-L-valyl-L-seryl-L-tryptophylglycyl-L-leucyl-L-arginine, YAPLPRWSGPIGVSWGLR

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关于此项目

经验公式（希尔记法）:
C96H142N26O22 · xC2HF3O2
化学文摘社编号:
1270083-24-3
分子量:
2012.32 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥95% (HPLC)
Form:
powder
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Quality Segment

100

assay

≥95% (HPLC)

form

powder

color

white to beige

shipped in

wet ice

storage temp.

−20°C

SMILES string

N3([C@@H](CCC3)C(=O)N[C@@H](CCCN\C(=N\[H])\N)C(=O)N[C@@H](Cc7c8c([nH]c7)cccc8)C(=O)N[C@@H](CO)C(=O)NCC(=O)N4[C@@H](CCC4)C(=O)N[C@@H]([C@H](CC)C)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc5c6c([nH]c5)cccc6)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@

InChI

1S/C96H142N26O22/c1-10-53(8)79(90(139)107-46-76(127)118-78(52(6)7)91(140)117-71(49-124)86(135)113-67(41-56-43-104-62-22-13-11-20-59(56)62)81(130)106-45-75(126)110-66(38-50(2)3)84(133)112-65(94(143)144)25-16-34-103-96(100)101)119-89(138)72-26-17-35-120(72)77(128)47-108-82(131)70(48-123)116-85(134)68(42-57-44-105-63-23-14-12-21-60(57)63)114-83(132)64(24-15-33-102-95(98)99)111-87(136)74-28-19-37-122(74)93(142)69(39-51(4)5)115-88(137)73-27-18-36-121(73)92(141)54(9)109-80(129)61(97)40-55-29-31-58(125)32-30-55/h11-14,20-23,29-32,43-44,50-54,61,64-74,78-79,104-105,123-125H,10,15-19,24-28,33-42,45-49,97H2,1-9H3,(H,106,130)(H,107,139)(H,108,131)(H,109,129)(H,110,126)(H,111,136)(H,112,133)(H,113,135)(H,114,132)(H,115,137)(H,116,134)(H,117,140)(H,118,127)(H,119,138)(H,143,144)(H4,98,99,102)(H4,100,101,103)/t53-,54-,61-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,78-,79-/m0/s1

InChI key

WMSPWLIEKXALQP-WSSJNERPSA-N

Biochem/physiol Actions

Spadin is a brain penetrant TREK-1 channel inhibitor that has antidepressant effects in mouse models of depression with a rapid onset of action.
Spadin is a brain penetrant TREK-1 channel inhibitor.
Spadin is a peptide derived from a propeptide released in blood upon Sortilin modification.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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