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SML1523

Estetrol

Name: Estetrol
Brand: SIGMA

≥98% (HPLC), selective estrogen receptor modulator, powder

别名:

15α-Hydroxyestriol, 3,15α,16α,17β-Tetrahydroxyestra-1,3,5(10)-triene, E4, Estra-1,3,5(10)-triene-3,15α,16α,17β-tetrol, Oestetrol

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关于此项目

经验公式（希尔记法）:

C₁₈H₂₄O₄

化学文摘社编号:

15183-37-6

分子量:

304.38

UNSPSC Code:

51111800

PubChem Substance ID:

329825940

NACRES:

NA.77

MDL number:

MFCD00198996

Assay:

≥98% (HPLC)

Form:

powder

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属性

产品名称

Estetrol, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

solubility

DMSO: 20 mg/mL, clear

storage temp.

−20°C

SMILES string

[H][C@@]12CCC3=CC(O)=CC=C3[C@@]1([H])CC[C@@]4(C)[C@@]2([H])[C@@H](O)[C@@H](O)[C@@H]4O

InChI

1S/C18H24O4/c1-18-7-6-12-11-5-3-10(19)8-9(11)2-4-13(12)14(18)15(20)16(21)17(18)22/h3,5,8,12-17,19-22H,2,4,6-7H2,1H3/t12-,13-,14-,15-,16-,17+,18+/m1/s1

InChI key

AJIPIJNNOJSSQC-NYLIRDPKSA-N

说明

General description

Estetrol is an estrogenic steroid molecule produced exclusively during pregnancy by the fetal liver.

Biochem/physiol Actions

Estetrol (E4, 15α-Hydroxyestriol) is an estrogen steroid hormone produced exclusively during pregnancy by the fetal liver.

Estetrol (E4, 15α-Hydroxyestriol) is an estrogen steroid hormone produced exclusively during pregnancy by the fetal liver. Estetrol is a selective estrogen receptor modulator (SERM) with potent estrogenic effects on vaginal mucosa, bone and brain, neutral effect on liver, and anti-estrogen effects on breast tissue. Estetrol has higher affinity for ERα over ERβ. Estetrol is being studied for its potential as a contraceptive, a drug for meopausal symptoms, and an anticancer agent.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c