主要文件

查看所有文档

SML1552

Tipiracil hydrochloride

Name: Tipiracil hydrochloride
Brand: SIGMA

≥98% (HPLC), thymidine phosphorylase inhibitor, powder

别名:

5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride, TPI hydrochloride

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₉H₁₁ClN₄O₂ · HCl

化学文摘社编号:

183204-72-0

分子量:

279.12

UNSPSC Code:

12352200

PubChem Substance ID:

329825960

NACRES:

NA.77

MDL number:

MFCD01571384

Assay:

≥98% (HPLC)

Form:

powder

Storage condition:

desiccated

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

产品名称

Tipiracil hydrochloride, ≥98% (HPLC)

Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H₂O: 5 mg/mL, clear (warmed)

storage temp.

2-8°C

SMILES string

[H]Cl.ClC1=C(CN2C(CCC2)=N)NC(NC1=O)=O

InChI

1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H

InChI key

KGHYQYACJRXCAT-UHFFFAOYSA-N

Gene Information

human ... TYMP(1890)

说明

Biochem/physiol Actions

Tipiracil is an inhibitor of thymidine phosphorylase.

Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil is used in combination with trifluridine as TAS-102 for the treatment of refractory metastatic colorectal cancer. Tipiracil increases the bioavailability of trifluridine by blocking the enzyme that would otherwise protect the tumors by metabolizing trifluridine.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000528537

0000528536