SML1552
Tipiracil hydrochloride
≥98% (HPLC), thymidine phosphorylase inhibitor, powder
别名:
5-Chloro-6-[(2-imino-1-pyrrolidinyl)methyl]-2,4(1H,3H)-pyrimidinedione hydrochloride, TPI hydrochloride
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About This Item
经验公式（希尔记法）:
C9H11ClN4O2 · HCl
CAS Number:
分子量:
279.12
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
Product Name
Tipiracil hydrochloride, ≥98% (HPLC)
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
white to beige
溶解性
H2O: 5 mg/mL, clear (warmed)
储存温度
2-8°C
SMILES字符串
[H]Cl.ClC1=C(CN2C(CCC2)=N)NC(NC1=O)=O
InChI
1S/C9H11ClN4O2.ClH/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11;/h11H,1-4H2,(H2,12,13,15,16);1H
InChI key
KGHYQYACJRXCAT-UHFFFAOYSA-N
基因信息
human ... TYMP(1890)
相关类别
生化/生理作用
Tipiracil is an inhibitor of thymidine phosphorylase.
Tipiracil is an inhibitor of thymidine phosphorylase. Tipiracil is used in combination with trifluridine as TAS-102 for the treatment of refractory metastatic colorectal cancer. Tipiracil increases the bioavailability of trifluridine by blocking the enzyme that would otherwise protect the tumors by metabolizing trifluridine.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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