SML1601
NSC59984
≥98% (HPLC)
别名:
(E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2yl)prop-2-en-1-one, 1-(4-Methyl-1-piperazinyl)-3-(5-nitro-2-furanyl)-2-propen-1-one, 1-Methyl-4-[3-(5-nitro-2-furanyl)-1-oxo-2-propenyl]-piperazine, CID 5356520, MLS000737358
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关于此项目
经验公式（希尔记法）:
C12H15N3O4
化学文摘社编号:
分子量:
265.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
InChI
1S/C12H15N3O4/c1-13-6-8-14(9-7-13)11(16)4-2-10-3-5-12(19-10)15(17)18/h2-5H,6-9H2,1H3/b4-2+
SMILES string
CN1CCN(C(/C=C/C2=CC=C([N+]([O-])=O)O2)=O)CC1
InChI key
QKTRIGNWBRHBFV-DUXPYHPUSA-N
assay
≥98% (HPLC)
form
powder
color
yellow to brown
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
NSC59984 targets various mutant p53 to restore wild-type p53 pathway via the activation of p73 in cancer cells.
NSC59984 targets various mutant p53 to restore wild-type p53 pathway via the activation of p73 in cancer cells. NSC59984 depletes a gain of function (GOF p53 mutants. NSC59984 is not cytotoxic against normal cells.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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