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Merck
CN

SML1616

ICA-069673

≥98% (HPLC)

别名:

ICA 069673, N-(2-Chloro-5-pyrimidinyl)-3,4-difluoro-benzamide

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关于此项目

经验公式(希尔记法):
C11H6ClF2N3O
化学文摘社编号:
分子量:
269.63
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
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Quality Segment

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

room temp

SMILES string

O=C(C1=CC=C(F)C(F)=C1)NC2=CN=C(Cl)N=C2

InChI

1S/C11H6ClF2N3O/c12-11-15-4-7(5-16-11)17-10(18)6-1-2-8(13)9(14)3-6/h1-5H,(H,17,18)

InChI key

IIBSHMFXVWTQSJ-UHFFFAOYSA-N

Biochem/physiol Actions

ICA-069673 has higher selectivity towards KV7.2/KV7.3 heterodimeric channels than KV7.3/KV7.5 channels. ICA-069673 is considered as a part of gating modifiers.
ICA-069673 is an orally active, potent and selective KV7.2/KV7.3 (KCNQ2/Q3) channel opener that is active in rodent epilepsy models.
ICA-069673 is an orally active, potent and selective KV7.2/KV7.3 (KCNQ2/Q3) channel opener.


存储类别

11 - Combustible Solids

wgk

WGK 3



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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