SML1623
MSP-3
≥98% (HPLC)
别名:
N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide
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关于此项目
经验公式（希尔记法）:
C16H19NO3S
化学文摘社编号:
分子量:
305.39
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
oil
Quality Segment
assay
≥98% (HPLC)
form
oil
color
white to beige
storage temp.
room temp
SMILES string
O=C(NCC1=CC=C(O)C(OC)=C1)CCCC2=CC=CS2
InChI
1S/C16H19NO3S/c1-20-15-10-12(7-8-14(15)18)11-17-16(19)6-2-4-13-5-3-9-21-13/h3,5,7-10,18H,2,4,6,11H2,1H3,(H,17,19)
InChI key
HCUVEUVIUAJXRB-UHFFFAOYSA-N
Biochem/physiol Actions
MSP-3 is a Transient Receptor Potential Vanilloid Type-1 (TRPV1) channel agonist with antioxidant and neuroprotective activity. MSP-3 activated TRPV1 channels with similar efficacy as compared to capsaicin (EC50 = 870 nM). It protected a keratinocyte cell line from oxidative stress damage with more efficacy than capsaicin and prevented the damage caused by H2O2 in differentiated human neuroblastoma cell lines as well as in rat cortical slices.
TRPV1 agonist protective against oxidative stress
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable