SML1669
NCX 4016
≥98% (HPLC)
别名:
2-(Acetyloxy)-benzoic acid 3-[(nitrooxy)methyl]phenyl ester, 2-Acetoxybenzoic acid 3-nitrooxymethylphenyl ester, 3-(Nitroxymethyl)phenyl 2-acetoxybenzoate, NCX-4016, Nitroaspirin
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C16H13NO7
化学文摘社编号:
分子量:
331.28
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
产品名称
NCX 4016, ≥98% (HPLC)
InChI
1S/C16H13NO7/c1-11(18)23-15-8-3-2-7-14(15)16(19)24-13-6-4-5-12(9-13)10-22-17(20)21/h2-9H,10H2,1H3
SMILES string
CC(OC1=CC=CC=C1C(OC2=CC(CO[N+]([O-])=O)=CC=C2)=O)=O
InChI key
IOJUJUOXKXMJNF-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 25 mg/mL, clear
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
Nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor
NCX-4016 can prevent the progression of cisplatin-resistant human ovarian cancer xenografts in mice. It can also regulate the expression of B-cell lymphoma 2 (Bcl-2) proteins in ovarian cancer cells. Hence, NCX-4016 is considered a promising therapeutic option against carcinoma.
NCX 4016 (nitroaspirin) is nitroderivative of aspirin that combines cyclooxygenase inhibitor with an NO donor. NCX 4016 improves postischemic ventricular dysfunction and to reduce myocardial infarct size in rabbit.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Karuppaiyah Selvendiran et al.
Cell cycle (Georgetown, Tex.), 7(1), 81-88 (2008-01-17)
We have previously reported the inhibitory effect of NCX-4016, a nitro derivative of aspirin, on the proliferation of cisplatin-resistant human ovarian cancer cells, in vitro (Bratasz et al., Proc Natl Acad Sci USA 2006; 103:3914-9). In this report we present
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持