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Merck
CN

SML1719

BPC 157 trifluoroacetate salt

≥95% (HPLC)

别名:

BPC-157, Booly Protection Compound 15, GEPPPGKPADDAGLV, Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

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关于此项目

经验公式(希尔记法):
C62H98N16O22 · xC2HF3O2
化学文摘社编号:
分子量:
1419.54 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
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InChI key

HEEWEZGQMLZMFE-RKGINYAYSA-N

SMILES string

N2([C@@H](CCC2)C(=O)N3[C@@H](CCC3)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N4[C@@H](CCC4)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)O)C(=O)[C@H]1N(CCC1)C(=O)[C@@H](NC(=O)CN)CCC(=O)O

assay

≥95% (HPLC)

form

film

color

colorless

shipped in

wet ice

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

BPC 157 is a gut peptide and possesses free radical scavenging activity. This peptide stimulates nitric oxide synthase generation and therefore offers gastric cytoprotection. Unlike other peptides, BPC 157 is effective without a carrier. It participates in muscle healing and is used in the treatment of gastrocnemius muscle complex.
BPC 157 is a stable gastric pentadecapeptide that exhibit anti-ulcer and wounds/fistulas healing properties.
BPC 157 is a stable gastric pentadecapeptide that exhibit anti-ulcer and wounds/fistulas healing properties. BPC 157 reduces immediate and delayed damage induced brain trauma and improves nerve regeneration after transection. BPC 157 displays antianxiety and antidepressant effects. It appears that BPC 157 promotes proliferation, migration, and tube formation of human umbilical vein endothelial cells through activation of ERK1/2 phosphorylation.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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The influence of a novel pentadecapeptide, BPC 157, on NG-nitro-L-arginine methylester and L-arginine effects on stomach mucosa integrity and blood pressure.
Sikiric P, et al.
European Journal of Pharmacology, 332(1), 23-33 (1997)
Gastric pentadecapeptide BPC 157 as an effective therapy for muscle crush injury in the rat.
Novinscak T, et al.
Surgery Today, 38(8), 716-725 (2008)

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