SML1792
恶唑黄
≥98% (HPLC), Fluorescent DNA-binding dye for apoptosis detection, powder
别名:
4-[（3-甲基-2 (3H)-苯并恶唑亚甲基）甲基]-1-[3-（三甲基氨）丙基]-喹啉二碘化物
Product Name
恶唑黄, ≥98% (HPLC)
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
protect from light
颜色
yellow to orange-brown
溶解性
H2O: 5, clear (warmed)
储存温度
2-8°C
SMILES字符串
CN1C2=CC=CC=C2OC1=CC3=CC=[N+](CCC[N+](C)(C)C)C4=C3C=CC=C4
InChI
1S/C24H29N3O.2HI/c1-25-22-12-7-8-13-23(22)28-24(25)18-19-14-16-26(15-9-17-27(2,3)4)21-11-6-5-10-20(19)21;;/h5-8,10-14,16,18H,9,15,17H2,1-4H3;2*1H/q+2;;/p-2
InChI key
ULHRKLSNHXXJLO-UHFFFAOYSA-L
生化/生理作用
恶唑黄是一种与 DNA 结合的荧光菁染料，用于检测凋亡细胞。恶唑黄不能进入活细胞。然而，在细胞凋亡过程中，细胞质膜变得轻微渗透，允许染料进入。恶唑黄常与碘化丙啶（CAT号P4170），这是一种 DNA 死亡细胞染色剂，既不会进入活细胞，也不会进入凋亡细胞。λEx/λ恶唑黄的电镜观察结果为 491/509。
染料检测凋亡细胞
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Andreas S Biebricher et al.
Nature communications, 6, 7304-7304 (2015-06-19)
DNA intercalators are widely used as fluorescent probes to visualize DNA and DNA transactions in vivo and in vitro. It is well known that they perturb DNA structure and stability, which can in turn influence DNA-processing by proteins. Here we
Sho Fujisawa et al.
Cytotechnology, 66(2), 259-273 (2013-09-26)
Radiofrequency (RF) ablation (RFA) is a minimally invasive treatment for colorectal-cancer liver metastases (CLM) in selected nonsurgical patients. Unlike surgical resection, RFA is not followed by routine pathological examination of the target tumor and the surrounding liver tissue. The aim
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